Resources

This Blueprint-funded Resource supports the design, creation, and characterization of Cre-recombinase-expressing ("Cre-Driver") mouse lines on the C57B1/6 background, which can be used to drive expression of reporter genes and conditional-ready alleles in the mouse nervous system. A MATLAB toolbox used in the paper that can be used to plug in other cell-type transcriptomes to infer their spatial distribution in the mouse brain.

clusterExperiment, an open source R package, provides functions for executing, evaluating and visualizing many different clusterings of experimental data, including data from single cell RNA-Seq studies.

Researchers from the Howard Hughes Medical Institute use high-speed light-sheet microscopy to image almost all neurons in the intact larval zebrafish brain at single-cell resolution, capturing activity in the entire brain once every 1.3 s. Source: Nature.

FastProject analyzes a gene expression matrix and produces a dynamic output report in which two-dimensional projections of the data can be explored. Annotated gene sets (referred to as 'signatures') are incorporated so that features in the projections can be understood in relation to the biological processes they might represent. FastProject provides a novel method of scoring each cell against a gene signature so as to minimize the effect of missed transcripts as well as a method to rank signature-projection pairings so that meaningful associations can be quickly identified.

The American Brain Coalition and NIH teamed up to host a BRAIN Initiative webinar for the patient advocacy community featuring Drs. Walter Koroshetz (Director, NINDS) and Joshua Gordon (Director, NIMH).

The objective of the BRAIN Initiative Advanced Postdoctoral Career Transition Award to Promote Diversity (K99/R00) is to enhance biomedical research workforce diversity and foster a strong cohort of new, highly skilled and well trained, NIH-supported, independent investigators from diverse backgrounds working in research areas supported by the BRAIN Initiative, as highlighted in BRAIN 2025: A Scientific Vision. This webinar is intended to assist participants in putting together their application.
Contact: lauren.ullrich@nih.gov

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The objective of the BRAIN Initiative Advanced Postdoctoral Career Transition Award to Promote Diversity (K99/R00) is to enhance biomedical research workforce diversity and foster a strong cohort of new, highly skilled and well trained, NIH-supported, independent investigators from diverse backgrounds working in research areas supported by the BRAIN Initiative, as highlighted in BRAIN 2025: A Scientific Vision. This webinar is intended to assist participants in putting together their application.
Contact: lauren.ullrich@nih.gov

This webinar will take you through the process of putting together an application for the NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award. The webinar will go through each part of the application, including eligibility, specific aims and research strategy, sponsor and co-sponsor information, letters of reference and support, and the certification letter. The second half of the webinar will be a question and answer session for attendees. This webinar was held on Wednesday, January 18, 2017.