A 5-dimensional connectomics approach to the neural basis of behavior

UNIVERSITY OF MASSACHUSETTS AMHERST
RFA-NS-18-008
2018
U01NS108637
KATZ, PAUL

The brain is constantly assessing information that guides decision making, which can be a matter of life or death. For example, animals can choose to go to a place filled with food or an area filled with predators. Dr. Katz and his team will examine how neural circuits allow the mollusk Berghia stephaniaedecide where to go, implementing this common decision behavior with fundamental, reductionist neural mechanisms. The group will start by creating a complete map of the Berghia nervous system, which will detail connections between neurons and sensorimotor structures, as well as gene expression in the cells, before exploring the cells and circuits involved in decision making related to navigation. This project will provide a new animal model for studying the nervous system in fundamental simplicity and will offer a broader understanding of the decision-making processes in more complex brain structures.

UNIVERSITY OF MASSACHUSETTS AMHERST Amherst , MA
United States
42° 22' 23.5992" N, 72° 31' 11.4744" W
Massachusetts US
9614766
Funded Status: 
Active