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The BRAIN Initiative

Funding Opportunities

Scientists funded by the NIH BRAIN Initiative will develop tools to simultaneously watch the unique firing patterns of many neurons in hopes of classifying them based on physical characteristics, such as size and shape, and functional characteristics, such as patterns of electrical activity.

Scientists funded by the NIH BRAIN Initiative will develop tools to simultaneously watch the unique firing patterns of many neurons in hopes of classifying them based on physical characteristics, such as size and shape, and functional characteristics, such as patterns of electrical activity. Credit: Vincent Pieribone, Ph.D., John B. Pierce Laboratory, Inc.


Coming Soon:

The following funding concepts have been approved and their release is anticipated by mid-January.

Active BRAIN Funding Opportunities

  • BRAIN Initiative: Development, Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42) (PAR-15-090) (New) - The purpose of this funding opportunity announcement (FOA) is to support the development of novel tools and technologies through the through the Small Business Technology Transfer (STTR) program to advance the field of neuroscience research, including 1) tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function, 2) proof-of-concept testing and development of new technologies and novel approaches for large scale recording and manipulation of neural activity, at or near cellular resolution, at multiple spatial and/or temporal scales, in any region and throughout the entire depth of the brain, and 3) iterative refinement of such tools and technologies with the end-user community with an end-goal of scaling manufacture towards reliable, broad, sustainable dissemination and incorporation into regular neuroscience practice.
    Application Receipt Date(s): Standard Dates Apply
    Contact Email: mgrabb@mail.nih.gov
  • BRAIN Initiative: Development, Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (SBIR) (R43/R44) (PAR-15-091) (New) - The purpose of this funding opportunity announcement (FOA) is to support the development of novel tools and technologies through the Small Business Innovation Research (SBIR) program to advance the field of neuroscience research including 1) tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function, 2) proof-of-concept testing and development of new technologies and novel approaches for large scale recording and manipulation of neural activity, at or near cellular resolution, at multiple spatial and/or temporal scales, in any region and throughout the entire depth of the brain, and 3) iterative refinement of such tools and technologies with the end-user community with an end-goal of scaling manufacture towards reliable, broad, sustainable dissemination and incorporation into regular neuroscience practice.
    Application Receipt Date(s): Standard Dates Apply
    Contact Email: mgrabb@mail.nih.gov
  • BRAIN Initiative: Short Courses in Computational Neuroscience (R25) (RFA-MH-15-215) (New) - This funding opportunity announcement (FOA) will support short courses to facilitate the development of a sophisticated cadre of investigators with the requisite knowledge and skills in computational neuroscience perspectives and techniques for analyzing and interpreting complex, high-dimensional neuroscience data to advance the BRAIN Initiative. For the purposes of this FOA, computational neuroscience encompasses theoretical neuroscience, computational and mathematical modeling of neural systems, and/or statistical perspectives and techniques. Each short course is expected to include both didactics and in-person/hands-on experiences. This FOA is intended for participants who are graduate students, medical students, postdoctoral scholars, medical residents, and/or early-career faculty.
    Application Receipt Date(s): March 18, 2015
    Contact Email: Erica.Rosemond@nih.gov
  • BRAIN Initiative: Short Courses in Research Tools and Methods (R25) (RFA-MH-15-220) (New) - This funding opportunity announcement (FOA) will support creative educational activities with a primary focus on Courses for Skills Development that will build participantsí foundational knowledge and skills in the rigorous use of state-of-the art scientific tools and methods that contribute to, and are developed in response to, the major goals of the BRAIN Initiative. Each short course is expected to include both didactics and in-person / hands-on experiences. This FOA is intended for participants who are graduate students, medical students, postdoctoral scholars, medical residents, and/or early-career faculty.
    Application Receipt Date(s): March 18, 2015
    Contact Email: Erica.Rosemond@nih.gov
  • BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (RFA-MH-15-225) (New)— This announcement supports development and validation of novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function.
    Application Receipt Date(s): March 18, 2015
    Contact Email: BRAIN-info-NIMH@mail.nih.gov
  • BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (U01) (RFA-NS-15-003) (New)— Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for large scale recording and manipulation of neural activity, to enable transformative understanding of dynamic signaling in the nervous system.
    Application Receipt Date(s): February 10, 2015
    Contact Email: NINDS-Brain-Initiative@nih.gov
  • BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01) (RFA-NS-15-004) (New)— Although invention and proof-of-concept testing of new technologies are key components of the BRAIN Initiative, to achieve their potential these technologies must also be optimized through feedback from end-users in the context of the intended experimental use. In this FOA we seek applications for the optimization of existing and emerging technologies and approaches that have potential to address major challenges associated with recording and manipulating neural activity, at or near cellular resolution, at multiple spatial and temporal scales, in any region and throughout the entire depth of the brain.
    Application Receipt Date(s): February 10, 2015
    Contact Email: NINDS-Brain-Initiative@nih.gov
  • BRAIN Initiative: Integrated Approaches to Understanding Circuit Function in the Nervous System (U01) (RFA-NS-15-005) (New)— The purpose of this FOA is to promote the integration of experimental, analytic, and theoretical capabilities for large-scale analysis of neural systems and circuits. This FOA seeks applications for exploratory research studies that use new and emerging methods for large scale recording and manipulation of neural circuits across multiple brain regions. Applications should propose to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system.
    Application Receipt Date(s): February 10, 2015 Program Announcements
    Contact Email: NINDS-Brain-Initiative@nih.gov

    Informational Conference Call information on RFA-NS-15-005 (Integrated Approaches to Understanding Circuit Function in the Nervous System (U01)):

    • Meeting Date and Time: Tuesday, 13 January, 2015, 1:00-2:00 PM Eastern.
    • Please email Karen David (karen.david@nih.gov) with any follow-up questions or comments.


  • BRAIN Initiative: Planning for Next Generation Human Brain Imaging (R24) (RFA-MH-15-200) (New)— This funding opportunity announcement (FOA), in support of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, aims to support planning activities and the initial stages of development of entirely new or next generation brain imaging technologies and methods that will lead to transformative advances in our understanding of the human brain.
    Application Receipt Date(s): March 18, 2015
    Contact Email: BRAIN-info-NIMH@mail.nih.gov

Frequently Asked Questions

Read our Applicant FAQs.

FY 2014 Opportunity Announcements

FY 2014 funding opportunities for the BRAIN Initiative are closed. New announcements will be posted when available.

NIH released six funding opportunities in early 2014 focused on advancing our technological capabilities for understanding how circuits of interacting neurons function to create behavior. There was a robust response; 340 applications were submitted, with 58 grants receiving funding (17.1% success rate).

NIH Awards Initial $46 million for BRAIN Initiative Research, September 30, 2014.
NIH announces Informational Conference Calls for Prospective Applicants, January 6, 2014
News release: NIH announces six funding opportunities for the BRAIN Initiative in fiscal 2014, December 17, 2013

 

THE BRAIN INITIATIVE and BRAIN RESEARCH THROUGH ADVANCING INNOVATIVE NEUROTECHNOLOGIES are service marks of the U.S. Department of Health & Human Services (HHS).

This page last reviewed on April 22, 2014